AstraZeneca Secures 10-Year Isotope Supply Deal to Fuel its Radiopharmaceutical Ambitions in Targeted Cancer Therapy

Pharmaceutical giant AstraZeneca has significantly expanded its partnership with Niowave, securing a decade-long supply of Actinium-225 (Ac-225) to bolster its growing pipeline of next-generation oncology treatments.

  • Agreement Details: By exercising its option to increase capacity, AstraZeneca ensures a reliable source of Ac-225 for its radioconjugate drugs. This isotope delivers potent alpha particles capable of destroying cancer cell DNA with high precision while minimizing damage to healthy tissue.

  • Strategic Integration: This 10-year commitment follows AstraZeneca’s $2 billion acquisition of Fusion Pharmaceuticals earlier in 2025, solidifying the company’s position in the high-stakes radiopharmaceutical market.

  • Technological Edge: Niowave leverages advanced superconducting linear accelerator technology to address the global shortage of medical isotopes, providing the essential ingredients for AstraZeneca’s clinical programs, such as prostate cancer therapies.

  • Market Context: The deal reflects a broader 2025 industry trend, where major players are aggressively securing raw materials and manufacturing facilities to stabilize the supply chain for cutting-edge targeted radiotherapies.

Source: https://www.fiercepharma.com/manufacturing/astrazeneca-extends-niowaves-radioisotope-supply-deal-another-decade

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