Eclipsebio acquires Terrain Bio to provide unified solutions for RNA therapeutics

Eclipse Bioinnovations Inc. (Eclipsebio), a leading provider of sequencing-based analytics for RNA medicines, has announced the acquisition of Terrain Bio, a tech-bio firm specializing in AI/ML-driven RNA design and manufacturing analytics.

Integrating design intelligence with experimental validation

This acquisition marks a strategic move to combine advanced computational capabilities with real-world data verification.

  • Terrain Bio’s expertise: The company has developed sophisticated machine learning models for RNA sequence optimization and an R&D-scale mRNA manufacturing platform that links computational design directly with experimental feedback.

  • Eclipsebio’s foundation: The firm contributes its established sequencing-based datasets and robust quality control platforms, such as eMERGE and eVERSE.

A unified “Design, Make, Test” solution

The combined platform enables RNA therapeutic developers to access a continuous improvement loop:

  1. Design: Iteratively optimize RNA constructs using AI modeling and active learning.

  2. Test: Measure structures, translation, and impurities through high-resolution sequencing analytics.

  3. Manufacture: Gain actionable insights into manufacturing robustness and quality-by-design.

This synergy bridges the gap between computational theory and experimental validation, helping RNA-based medicines reach clinical stages faster and with enhanced confidence.

Source: https://www.contractpharma.com/breaking-news/eclipsebio-acquires-terrain-bio/

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