Corxel Pharmaceuticals secures $287m to advance cardiometabolic pipeline

Major financial milestone via Series D1 funding On January 23, 2026, Corxel Pharmaceuticals announced the closure of a $287 million Series D1 financing round. The funding attracted new institutional investors, including SR One, TCGX, and RA Capital Management, alongside continued support from existing backers like RTW Investments. This substantial raise highlights the persistent investor enthusiasm for the obesity and weight-loss drug sector.

Clinical progress of lead candidate CX11 The primary focus of this investment is the development of CX11, an oral glucagon-like peptide-1 receptor agonist (GLP-1RA). The drug is currently moving through high-stakes clinical trials:

  • United States: Currently in Phase II clinical evaluation.

  • China: Progressing through Phase III trials (overseen by Vincentage).

Earlier clinical data released in June 2025 indicated that patients on a fast-titration schedule of the highest dose achieved a 9.7% reduction in body weight over a 16-week period.

Broader pipeline and market outlook Beyond obesity management, Corxel is allocating funds to advance other cardiometabolic assets, including:

  • JX10: A pro-thrombolytic candidate for acute ischemic stroke.

  • JX09: An aldosterone synthase inhibitor targeting hypertension.

The global obesity market across the seven major markets (7MM) is projected to soar to $173.5 billion by 2031. Corxel’s funding success follows a trend of massive capital injections into the sector, mirroring recent high-profile deals involving firms like Kailera and Metsera as the industry races to compete with incumbents like Eli Lilly and Novo Nordisk.

Source: https://www.pharmaceutical-technology.com/news/corxel-raises-287m-as-obesity-continues-to-spark-investor-interest/?cf-view

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