Responding to the rise of at-home patient care, Datwyler has launched a first-to-market universal plunger designed for large-volume cartridges of up to 20mL. This addition to the NeoFlex line is specifically engineered for on-body subcutaneous delivery systems used in high-dose biotherapeutics.
Overcoming Barriers in Biologic Delivery While most biologics currently require lengthy intravenous administration at healthcare facilities, there is a growing shift toward self-administered subcutaneous delivery. However, this transition faces hurdles such as formulation complexities and a lack of standardized components.
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Development Efficiency: Datwyler’s “pre-verified solution” aims to help pharmaceutical companies bypass manufacturing obstacles, potentially saving up to three years in development time.
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Controlled Delivery: The plunger enables slow, steady drug administration across various delivery devices, enhancing the patient experience for high-dose therapies.
Technical Innovation and Quality Assurance The plunger features a specialized fluoropolymer coating that eliminates the need for fluorosurfactants, providing a barrier against extractables, leachables, and other potential contaminants.
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Dosing Accuracy: Consistent and minimal gliding forces ensure that patients receive precise dosages every time.
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Manufacturing Standards: To mitigate risks, the components are produced in automated cleanroom environments equipped with high-precision camera inspection systems.
Source: https://www.contractpharma.com/breaking-news/datwyler-launches-industry-first-large-volume-plunger/